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Most vaccines probably do not prevent omicron infection

Numerous preliminary studies show that the Qovid vaccines, which are used in most parts of the world, offer almost no protection against infection caused by the highly contagious species of omicron. However, not all vaccines appear to provide adequate protection against severe omicron-induced disease.

Only Pfizer and Modern vaccines seem to be successful in stopping infections when boosted with a booster dose; But these vaccines are not available in most parts of the world. Preliminary research shows that other vaccines, including Astraznka and Johnson & Johnson, and vaccines made in China and Russia do not help inhibit the spread of omicron. Because most countries have developed their own vaccination plans based on these vaccines, this gap can have a profound effect on the globalization process.

The global increase in infections in a world where billions of people have not yet been vaccinated threatens not only the health of vulnerable people; It also increases the chances of new species emerging. Inequality in the ability of countries to tolerate globalization will deepen, and news of the limited efficacy of vaccines against omicron infection could reduce the demand for vaccination in developing countries.

Most of the evidence so far has been based on laboratory experiments that do not cover the full range of the immune response and have not been traced to its effects on real-world populations; However, the results are relevant. Pfizer and modern vaccines use new mRNA technology that has so far provided the best protection against all species. Older methods of stimulating the immune response have been used to make other vaccines.

The protection of the Chinese vaccines Sinofarm and Sinovac, which make up almost half of all vaccines available worldwide, against zoonotic infections is almost zero. An initial study of efficacy in the UK showed that six months after vaccination, the Oxford Astrazneka vaccine failed to inhibit omicron infection.

Researchers predict that Russia’s Sputnik vaccine will also show a lower rate of protection against omicrone. Demand for the Johnson & Johnson vaccine has been rising in Africa; Because it is offered in a single dose, this facilitates its delivery to resource-limited environments. However, the vaccine has also shown little ability to inhibit omicron infection.

Antibodies are the first line of defense that vaccines trigger; But vaccines also stimulate the growth of T cells. Preliminary studies show that these T cells continue to detect the omicron species, which is important for preventing severe disease. However, according to experts, this protection will not be enough to prevent the destructive effect of omicrons in the world; This is because the widespread scale of the infection will put pressure on health systems as the number of patients increases.

People with infections that occur after receiving the vaccine may experience an asymptomatic infection or a mild illness; But they can spread the virus to unvaccinated people. These individuals may become severely ill and become a source of new species.

the doctor Set BerkeleyThe executive director of the World Vaccine and Immunization Alliance said more data was needed before conclusions could be drawn about the effectiveness of vaccines against omicrone, and that accelerating vaccination should continue to be the focus of the global response. Preliminary data from South Africa show that compared to previous species, omicrons are more likely to be re-infected in people who have already had Covid.

Some experts believe that countries such as Brazil and India, which have already experienced strong Covid waves, may have a shield against the omicron, and vaccination after infection produces high levels of antibodies. Raman Lakshmi Narayan“The combination of vaccination and exposure to the virus seems to be stronger than the vaccine alone,” said epidemiologist in New Delhi. He noted that the adult vaccination rate in India is only about 40%; But in some areas, the rate of virus exposure has been 90%.

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China does not have such a protective layer to support its weak vaccines. Due to China’s aggressive efforts to stop the spread of the virus within its borders, relatively few people have been infected before. It is estimated that 7% of people in Wuhan, where the birth began, became infected.

Most Latinos rely on Chinese, Russian, and Astrazhenka vaccines. Mario Rosemblatt“More than 90 percent of Chileans have received two doses of the same vaccine, most of which was made by Sinovac,” said a professor of immunology at the University of Chile.

Rosmeblatt said the impressive coverage of the vaccine, with initial reports that omicron did not cause serious illness, would lead to a false sense of security in the country; But people need to know that this is not the case. If the transfer rate increases, the health system becomes saturated; Because more people get sick.

Brazil has also recommended that all vaccinated people receive the third dose and uses the Pfizer vaccine as a booster; But only 40% of vaccinated people come in to get their extra dose. Stephen Morrison, Director of the Center for Global Health Policy at the US Center for Strategic and International Studies, called Omicron’s ability to evade vaccination protection a major setback for low- and middle-income countries still delivering the first doses of vaccines.

For example, only 13% of Africans have received at least one dose of Covid vaccine. Morrison said the news that non-mRNA vaccines offer little protection against omicron-induced infection may reduce demand for the vaccine, which could impair the overall value of the vaccine and lead to mistrust of the vaccine.

the doctor تلبرت نینسوا He was deputy health minister at the time of Eberla’s worst outbreak in Liberia, and predicted that as a result, dangerous species from low-vaccination areas would continue to emerge, prolonging globalization. Dr. Berkeley said it is a big mistake for countries to reduce vaccination pressures or to assume that only mRNA vaccines are worth distributing. He added:

We may see a situation in which countries say: If developed countries do not want these vaccines; So we do not want them either. If these vaccines are found to prevent severe illness and death, this would be a misinterpretation.


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