How old are we really?

Sinclair is an influential and often marginalized researcher in the field of antiaging research. One of his jobs is promoting reserato, a compound in red grapes that he once likened to a miracle molecule. Other researchers are cautious about the compound’s possible benefits, given the results of the reservatrol compound in animal tests. Sinclair takes resveratrol supplements daily and is researching the compound. Also, he is the founder of biotech companies, including companies focused on longevity, and his book “Longevity: Why Are We Getting Old and Why Shouldn’t It?” It is on the New York Times bestseller list.

Melanie Goldie, CEO of Talley Health, talks about his company’s efforts to change the aging process. A number tells you how old you are; While another number only counts the number of your birthdays. According to Goldie, biological age is approximately six months less than historical age.

to report WiredIn addition to reading each client’s age and age, Taki Health provides a practical program of customized lifestyle recommendations such as sleeping more, sitting less, reducing stress or eating more vegetables. Users can take a test for $229 or check their biological age over time with a quarterly subscription plan. According to Goldi, users can make the necessary changes in their lifestyle by using the activity plan obtained based on the information.

When TakiHealth was founded, more than 270,000 people signed up and were placed on a waiting list, Goldie said, though he didn’t say exactly how many people signed up for the membership plan, which costs between $129 and $199 a month.

Like other epigenetic tests, TakiHealth examines DNA methylation patterns. Methylation refers to chemical tags on the DNA code that affect gene activity. In the 1970s, scientists established a link between DNA methylation and aging. In 2013, Steven Horvath, a geneticist and biostatistician at UCLA, published the first epigenetic aging clock based on these changes. This predictive test watch is based on data from 8,000 biological samples from 51 types of healthy human cells and tissues, which measures DNA methylation patterns associated with aging and disease, and uses an algorithm to estimate people’s age.

The next wave of epigenetic clocks went one step further in predicting how long a person will live or how many healthy years they will live. One of these watches was PhoneAge in 2018 Morgan Levine He published it from Yale University. Based on blood samples, this watch predicts the risk of overall mortality and the risk of cancer, cardiovascular diseases and Alzheimer’s. A year later, a group led by Horvath and Ek Loreleased GrimAge, an improved version of the group’s older clock that could predict a person’s remaining lifespan or death based on a blood sample.

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